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Last Updated: Sep 2009
What is Stomach Cancer?
A very small percentage of diffuse-type gastric cancers (see Histopathology below) are thought to be genetic. Hereditary  Diffuse Gastric Cancer (HDGC) has only recently been identified and research is ongoing, but genetic testing and treatment  options are available for families at risk.

Metastasis occurs in 80-90% of individuals with stomach cancer, with a five year survival rate of 75% in those diagnosed in  early stages and less than 30% of those diagnosed in late stages. The death rate is 12,400 a year in the United States.

Like any cancer, treatment is adapted to fit each person's individual needs and depends on the size, location, and extent of  the tumor, the stage of the disease, and general health. Cancer of the stomach is difficult to cure unless it is found in an  early stage (before it has begun to spread). Unfortunately, because early stomach cancer causes few symptoms, the disease is  usually advanced when the diagnosis is made. Treatment for stomach cancer may include surgery, chemotherapy, and/or radiation  therapy. New treatment approaches such as biological therapy and improved ways of using current methods are being studied in  clinical trials.
Stomach cancer (also called gastric cancer) can develop in any part of the stomach and may spread throughout the stomach and  to other organs; particularly the esophagus and the small intestine.

Stomach cancer represents roughly 2% (25,500) cases of all new cancer cases yearly in the United States, but it is much more  common in Japan, Great Britain, South America, and Iceland. It is associated with high salt in the diet, smoking, and low  intake of fruits and vegetables. Infection with H. pylori is the main risk factor in about 80% or more of gastric cancers. It  is more common in men.

Gastric or stomach cancer, has very high incidence in Korea and Japan. Gastric cancer is the leading cancer type in Korea  with 20.8% of malignant neoplasms, the second leading cause of cancer deaths. It is suspected several risk factors are  involved including diet, gastritis, intestinal metaplasia and Helicobacter pylori infection. A Korean diet high in salted,  stewed and broiled foods are expected to be a contributing factor. Ten percent of the cases show genetic components. In Japan  and other countries bracken consumption and spores are correlated to stomach cancer incidence. Epidemiologists have yet to  fully account for the high rates of gastric cancer as compared to other countries.
Stomach Cancer
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